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Cette vitamine B12 va alors se lier au facteur intrinsque , aussi appel facteur intrinsque de Castle, en lhonneur du scientifique William Castle, que nous avons dj mentionn et qui a ralis des travaux importants sur le sujet

In another study 13 of patients with known pernicious anemia who had not received maintenance vitamin B 12 injections for months to years, the rise of methylmalonic acid and homocysteine levels was found to precede the decrease in serum vitamin B 12 and the decline in hematocrit

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