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For most patients with congenital GHD, GH therapy will lead to significant catch-up growth but in patients with radiation induced GH deficiency catch up growth is rare (228,229)

Participants were excluded if they were being actively treated for sleep disorders, self-reported illicit substance usage, reported excessive consumption of alcohol or caffeine, had major or unstable psychiatric disorders or cognitive impairment as evaluated by the sleep physician/psychologist, were shift-workers, had transmeridian travel in the past 2 months (two or more time zones traversed) or were pregnant or lactating

otherwise, its effect remained limited (e.g., with low S content but abundant mesopores exhibited superior performance 89 )