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Video Review: Type I Hypersensitivity Reactions Block 3, Question 7 Explanation Correct Answer: E

Zhou et al., 2022

L nephritis (LN) was detected in 192 (48%) patients, SLE with antiphospholipid syndrome (APS) in 48 (12%), SLE with Sjogren's syndrome in 44 (11%)
Optic nerve injection of lysophosphatidylcholine (LPC) induced localized myelin loss in MS mice, significantly elevating Fe 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue
