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To evaluate this property, we systematically characterized its biodegradation behavior in PBS at pH 5.4 (simulating the lysosomal compartments), pH 6.5 (mimicking the OA pathological microenvironment), and pH 7.4 (representing normal physiological conditions)

This assessment guides the selection and timing of peptide interventions for optimal individual outcomes

Jankovic J, Stacy M
E.2010Investigation of Crosstalk BetweenWnt and Hedgehog Signaling Pathways in fly, MSc Thesis, Bogaziiniversitesi, Istanbul
