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Gene Expression Modulation Transcriptomic analyses in cellular models have shown that GHK-Cu influences expression of a remarkably wide set of genes, with reported effects on pathways involved in: Extracellular matrix remodeling DNA repair Antioxidant response Inflammatory signaling Stem cell signaling markers This broad transcriptional footprint has been one of the most studied aspects of GHK-Cu in recent years

Chronic use of these substances is strongly associated with persistent cognitive deficits, psychiatric symptoms, and, in some cases, neurovascular damage

Penuel E, Li C, Parab V, Burton L, Cowan KJ, Merchant M, et al