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10.1073/pnas.1416940111 [DOI] [PMC free article] [PubMed] [Google Scholar] 35.Voigt RG, Mellon MW, Katusic SK, Weaver AL, Matern D, Mellon B, et al
Loren Pickart estimated toxic action starting at approximately 22,500 mg (300-fold above effective doses), though some users report mild blood pressure effects even at normal doses
PLoS One 2014
The bottom line While the jury is still out on whether these pre-alcohol products can actually prevent a hangover, there are other concerns related to how they might affect someones drinking habits
