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Moreover, a decrease in phosphocholine cytidylyltransferase and PLA2 expression has been documented in the postmortem brains of individuals who abused cocaine and MA 59 , and reduced levels of PLA2 have been observed in the brains of rats subjected to chronic cocaine administration 60

Pyridoxine serves as an essential precursor to pyridoxal phosphate (PLP), a crucial enzyme cofactor heavily scrutinized in cellular transamination assays

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