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Glutathione S-transferases (GSTs) catalyze the conjugation of GSH to a broad range of electrophilic compounds, including endogenous signaling molecules, reactive aldehydes such as 4-hydroxynonenal (4-HNE), and heavy metals 13,14

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Although this risk was increased when taken with other drugs that impact the liver, signs of liver injury were seen also in patients not on those drugs
