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HIF-1 induces epithelial-mesenchymal transition (EMT), which further enhances the ability of tumor cells to tolerate hypoxia, locally invade, infiltrate blood vessels, and survive in peripheral blood vessels (171)

Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes

Polyplex systems comprise cationic polymers such as poly-L-Lysine (PLL), poly-L-ornithine (POL), polyethyleneimine (PEI), polyamidoamine (PAM) or combinations thereof with DNA

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