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Eosinophilic crystals have been described in intrahepatic bile ducts and gallbladder of different laboratory mice strains, and some of these crystals have been shown to contain chitinase-like proteins confirmed by immunohistochemistry for Ym1 protein (now Chi313) (Ward et al

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22 FIG.and 23 a FIG.show: ( 23 b FIG.) RSSH generation from 7b (100 M) in the presence of NAC (500 M) in pH 7.4 ammonium bicarbonate (50 mM) with DTPA (100 M) at 37 C