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Description
Duloxetine Evidence from preclinical [58, 59] and clinical studies [4] suggests that duloxetine, an antidepressant drug acting as a serotonin-noradrenaline reuptake inhibitor (SNRI), may be effective in the prevention of CIPN without reducing the antitumor activity of oxaliplatin [49]
via C-X-C chemokine receptor 1 (CXCR1) receptors
Blood 128 , 265276 (2016)
Evidence from animal models and in vitro experiments provides substantial support for the contribution of ferroptosis to PD pathogenesis
