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Description
Who Is the Right Candidate for Tesofensine
The mechanism appears to involve increased serotonin synthesis in substantia nigra (both compacta and reticulata), a regional pattern unlike any existing antidepressant drug, plus potential dopaminergic contributions given the nigrostriatal location
Patients were encouraged to receive their second dose
Current theories suggest a combination of several mechanisms, including autoimmune, genetic, inflammatory, and oxidative stress components (Xie et al., 2016
