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This additive effect suggests the compound enhances the benefits of physical training
doi: 10.1126/scisignal.abb7209 120 MorettiLStalfortJBarkerTHAbebayehuD
Polyphenolic compounds such as tannins diminish the digestibility of food by binding to gastric enzymes and dietary proteins, as compared to a controlled diet (122)
However, other studies suggest that cyclosporin A upregulates gingival SHH (Sonic hedgehog protein) expression in vitro, while in vivo that inhibition of the SHH pathway counteracts the stimulatory effect of cyclosporin A on gingival fibroblast proliferation
