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[DOI] [PubMed] [Google Scholar] 28.Nauck MA, et al

Nausea, vomiting, and gastrointestinal issues are well-documented

406,407 GLP-1RAs can alleviate neuroinflammation by acting on the nervous system, thereby offering additional relief from pain in patients

While this supports immune cell activation and enhances pathogen clearance, excessive activation may contribute to tissue injury and immunosuppression (52)