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Our study demonstrates that STZ-induced DNP led to a significant increase in the serum levels of all three pro-inflammatory cytokines TNF-, IL-1 and IL-6, and our findings align with prior research indicating that uncontrolled hyperglycemia triggers a series of inflammatory responses in STZ-DNP rats [55]

Anyone with type 2 diabetes needing better glucose control, individuals with obesity or weight-related health risks, or those with cardiovascular or kidney concerns should consult a doctor before using GLP-1 RAs

(C) Immunofluorescence of -endorphin (-end, green) and 4,6-diamidino-2-phenylindole (DAPI

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