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On the contrary, there are no data to suggest that CRP is the direct cause of any disease, whereas CRP infused in relatively healthy human adults does not trigger any significant clinical, hematologic, coagulative, or biochemical alterations, or any increase in proinflammatory cytokines or acute phase proteins [113]

Later observations confirmed that these domains bear key biophysical hallmarks of ordereddisordered liquid phase separation, including domain coalescence and temperature-dependent, reversible demixing (Rayermann et al., 2017)

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